microbiota

Capturing the diversity of the human milk microbiota through culture-enriched molecular profiling: a feasibility study

Previous human milk studies have confirmed the existence of a highly diverse bacterial community using culture-independent and targeted culture-dependent techniques. However, culture-enriched molecular profiling of milk microbiota has not been done. …

Breastmilk feeding practices are associated with the co-occurrence of bacteria in mothers’ milk and the infant gut: the CHILD Cohort Study

Gut microbiota play a critical role in infant health. It is now accepted that breastmilk contains live bacteria from endogenous and exogenous sources, but it remains unclear if these bacteria transfer to the infant gut and whether this process is …

Abnormal food timing promotes alcohol associated dysbiosis and colon carcinogenesis pathways

**Background:** Alcohol consumption is an established risk factor for colon cancer (CRC). Identifying cofactor(s) that modulate the effect of alcohol on colon inflammation and carcinogenesis could help risk stratification for CRC. Disruption of …

Integrated Analysis of Human Milk Microbiota with Oligosaccharides and Fatty Acids in the CHILD Cohort

**Background:** Human milk contains many bioactive components that are typically studied in isolation, including bacteria. We performed an integrated analysis of human milk oligosaccharides and fatty acids to explore their associations with milk …

Composition and Variation of the Human Milk Microbiome is Influenced by Maternal and Early Life Factors

Breastmilk contains a complex community of bacteria that may help seed the infant gut microbiota. The composition and determinants of milk microbiota are poorly understood. Among 393 mother-infant dyads from the CHILD cohort, we found that milk …